WebThe traditional view of follicle-stimulating hormone (FSH) as a reproductive hormone is changing. It has been shown that FSH receptors (FSHRs) are expressed in various extra-gonadal tissues and mediate the biological effects of FSH at those sites. Molecular, animal, epidemiologic, and clinical data suggest that elevated serum FSH may play a significant … WebAug 1, 2024 · The rise of follicle-stimulating hormone (FSH) is a hallmark of menopause associated with osteoporosis and visceral adiposity. In Nature, Zaidi and colleagues (Liu et al., 2024) report that blocking FSH action reduces body fat by promoting brown/beige fat thermogenesis, potentially providing a new intervention for the treatment of menopause …
Women are more susceptible to Alzheimer’s Dis EurekAlert!
WebA polyclonal antibody that targets the β-subunit of the pituitary hormone follicle-stimulating hormone (Fsh) increases bone mass in mice. Here, we report that this antibody sharply reduces adipose tissue in wild-type mice, phenocopying genetic haploinsufficiency for the Fsh receptor gene Fshr. WebMar 2, 2024 · Blocking FSH action prevents bone loss, fat gain and AD–like features in mice. We recently developed a first–in–class, humanized, epitope–specific FSH … asos petite online
Follicle-Stimulating Hormone (FSH): What It Is & Function
WebJul 12, 2024 · Blocking ovarian function: Because the ovaries are the main source of estrogen in premenopausal women, estrogen levels in these women can be reduced by … WebNov 4, 2024 · In the most recent study, researchers explain the development of a “humanized” monoclonal antibody to block FSH signaling. “This next stage brings us … WebDec 17, 2024 · Notably, blocking FSH signaling by anti-FSHβ antibody or ablating the Fshr gene could prevent cholesterol accumulation induced by elevated FSH or a high-cholesterol diet. This study provides new insights into hypercholesterolemia in menopausal females and shows that the inhibition of FSH signaling may be a new therapeutic strategy for ... lake tulane avon park