Cisplatin and electrolytes

Author: kdhw

August undefined, 2024

WebSep 23, 2024 · Background Cisplatin is an important drug in the treatment of various Cancers. However, this drug causes nephrotoxicity that is linked to electrolyte derangement. The aim of this study was to evaluate the effect of electrolyte supplementation in reducing kidney injury in patients receiving cisplatin-based regimen.

Side Effects of Lasix (furosemide), Warnings, Drug Interactions

WebCisplatin is a potent antineoplastic agent derived from platinum and commonly used in the treatment of head and neck, bladder, ovarian, and testicular malignanc Cisplatin-Induced Acute Kidney Injury and Renal Salt Wasting Syndrome Federal Practitioner WebPrevention and management of cisplatin nephrotoxicity. ID: 184 v.3. Endorsed. This document is an evidence based summary to complement treatment protocols and includes background and rationale for specific point of care actions. It is not intended to be a comprehensive literature review of all available evidence. port whale watching

184-Prevention and management of cisplatin …

WebApr 15, 2024 · Additionally, cisplatin-induced nephrotoxicity led to the unmasking of a familial form of hypomagnesemia. ... Previously, the baseline electrolyte profile was … WebSep 26, 2024 · While generally mild electrolyte deficiencies are pretty benign, moderate/severe abnormalities can cause many life-threatening conditions, including cardiac arrhythmias, seizures, muscle paralysis, … WebJul 20, 2024 · Platinum chemotherapy, particularly cisplatin, is commonly associated with electrolyte imbalances, including hypomagnesemia, … irons lubbock isd

(PDF) Incidence and spectrum of electrolyte disturbances …

Cisplatin SpringerLink

WebEffects on serum and tissue electrolytes The effects of cisplatin and spironolactone treatments on the serum electrolyte concentrations are summarized in Table 2. The serum magnesium was significantly elevated in the S and SP groups by 93.75 and 112%, respectively compared to control. Whereas that of the P group was WebAug 17, 2024 · The atrial natriuretic peptide (ANP), a cardiovascular hormone, plays a pivotal role in the homeostatic control of blood pressure, electrolytes, and water balance and is approved to treat congestive heart failure. In addition, there is a growing realization that ANPs might be related to immune response and tumor growth. The anti … irons nephew in house of gucciWebCisplatin and ifosfamide can cause kidney damage. This can be lessened by giving lots of fluids (usually into a vein – IV) before and after these drugs are given. Cisplatin, etoposide, paclitaxel, and vinblastine can damage nerves (known as neuropathy ). This can lead to numbness or tingling in the hands and feet, and sensitivity to cold or heat. port whitby ontario

"WebCisplatin solution for injection: Clear, practically colourless solution in amber glass vials containing cisplatin 1mg/ml, sodium chloride 9mg/ml and mannitol 1mg/ml with a pH of 3.5-4.0. 2 SUMMARY The principal target organ for cisplatin toxicity is the kidney. " - Cisplatin and electrolytes

Cisplatin and electrolytes

A Clinician’s Guide to Inpatient Electrolyte Replacement

WebApr 15, 2024 · Additionally, cisplatin-induced nephrotoxicity led to the unmasking of a familial form of hypomagnesemia. ... Previously, the baseline electrolyte profile was normal. He was suspected to have nephrotoxicity complicated by acute hypomagnesaemia. Hence, the boy was treated with supplementation and hypomagnesaemia recovered … WebMay 18, 2024 · Fluid, electrolyte and acid-base disorders associated with antibiotic therapy. Nat Rev Nephrol 2009; 5:193. Canada TW, Weavind LM, Augustin KM. Possible liposomal amphotericin B-induced nephrogenic diabetes insipidus. Ann Pharmacother 2003; 37:70. Sacks P, Fellner SK. Recurrent reversible acute renal failure from amphotericin.

Did you know?

WebSep 18, 2024 · Cisplatin is a medication used to manage and treat solid tumors and hematologic malignancies. It is in the alkylating agent class of cytotoxic medications. This activity reviews the indications, action, and contraindications for cisplatinum as a valuable agent in treating malignancy. WebNational Center for Biotechnology Information

WebNov 12, 2024 · Commonly reported side effects of cisplatin include: bone marrow depression, nephrotoxicity, and ototoxicity. Continue reading for a comprehensive list of … WebCisplatin revealed higher cytotoxicity towards established cell lines. Following CisEP application, we observed a significant decrease of cells viability in the primary culture …

WebFeb 16, 2016 · Purpose: Loco-regional control and organ preservation are significantly improved with concomitant cisplatin/radiotherapy and are compromised with less than 5% grade 3 nephrotoxicity (creatinine clearance 15–29 mL/min). However, although clinically important, in none of the randomized trials is grade 2 nephrotoxicity (defined as … WebNephrotoxicity: cisplatin for injection can cause severe renal toxicity, including acute renal failure. Severe renal toxicities are dose-related and cumulative. Ensure adequate …

WebElectrolyte imbalances and Cisplatin — Cancer Survivors Network Home › Head and Neck Cancer Electrolyte imbalances and Cisplatin buzz99 Member Posts: 404 October 2010 …

WebCisplatin is a potent and valuable chemotherapy agent used to treat a broad spectrum of malignancies. Renal tubular dysfunction and a cumulative impairment in kidney function, … irons mill farmstead new wilmington paWebJun 8, 2024 · Cisplatin injection, is a clear, colorless to pale yellow, sterile aqueous solution available in sterilie multiple-dose vials containing - 50 mg/50 mL (1 mg/mL) 100 mg/100 mL (1 mg/mL) 4 CONTRAINDICATIONS Cisplatin injection is contraindicated in patients with severe hypersensitivity to cisplatin - [see Warnings and Precautions ( 5.4) ... port width mismatchWebPaclitaxel and carboplatin are the names of a chemotherapy combination that includes: Paclitaxel (taxol) - P. Carboplatin - C. It is often called CarboTaxol or PC. It is a treatment for a number of different cancer types. You might have paclitaxel and carboplatin on its own, with other chemotherapy drugs or radiotherapy for some cancer types ... port whmWebMar 1, 2024 · Lasix is a strong diuretic that increases urination and relieves excess fluid from the body. This may also lead to the depletion of certain electrolytes, such as potassium. 5. Tips Dosages vary from individual to individual and people taking high dosages may need extra monitoring by their doctor. port whitby rentalsWebSep 21, 2024 · Common side effects of furosemide include low blood pressure, dehydration, electrolyte depletion, yellowing of skin and eyes (jaundice), ringing in the ears (tinnitus), sensitivity to light, rash, pancreatitis, nausea, diarrhea, abdominal pain, dizziness, increased blood sugar, and increased uric acid levels. port whiteWebJan 1, 2015 · Background: Cisplatin, one of the most commonly used chemotherapeutic agents, has electrolyte imbalances as one of its most important adverse effects. We conducted this study to characterize... port wholesaleWebThe primary outcome was to compare the rate of grade 3 or greater serum creatinine (SCr) increase in patients receiving saline hydration vs. the addition of mannitol; additional parameters of interest included creatinine clearance, electrolyte disturbances, dose changes, and discontinuation of cisplatin. port wholesalers