Phospho-sting

Author: lozf

August undefined, 2024

WebThe Mouse Phospho-STING (Ser365) assay measures mouse STING when phosphorylated at Ser365. Unlike Western Blot, the assay is entirely plate-based and does not require gels, electrophoresis, or transfer. The Mouse Phospho-STING (Ser365) assay uses 2 labeled antibodies: one with a donor fluorophore, the other one with an acceptor. WebCell Signaling Technology's Phospho-STING (Ser366) (D8K6H) Rabbit mAb (Alexa Fluor ® 647 Conjugate) is a Rabbit monoclonal antibody. The Phospho-STING (Ser366) (D8K6H) Rabbit mAb (Alexa Fluor ® 647 Conjugate) Antibody was generated using stimulator of interferon response cGAMP interactor 1, and STING1 as the antigen. It reacts with …

Mouse-Reactive STING Pathway Antibody Sampler Kit

WebApr 8, 2024 · In mammalian cells, this task is contributed in large part by the cyclic GMP–AMP synthase (cGAS)–stimulator of interferon genes (STING) pathway, which has emerged as a critical mechanism for... WebThe roles of phosphoinositide second messengers as signaling molecules in a vast array of cellular processes including cell growth, metabolism, vesicular transport, programmed … dark cherry wood king size headboard

4 Human Monocyte STING Activation Flow Cytometry Panel

WebThe interaction between STING and NCOA4 exacerbates lethal sepsis by orchestrating ferroptosis and inflammatory responses in macrophages. In Cell Death & Disease on 28 July 2024 by Wu, J., Liu, Q., et al.. WebPolyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser366 of human STING protein. Antibodies are purified by protein A and peptide affinity chromatography. Validations. None provided. Applications. Immunoprecipitation (IP) Western Blotting (WB) Reactivity. Homo sapiens … WebThe Mouse Phospho-STING (Ser365) assay measures mouse STING when phosphorylated at Ser365. Unlike Western Blot, the assay is entirely plate-based and does not require gels, … bisdee street coral cove

Phospho-sting

ER-lysosome lipid transfer protein VPS13C/PARK23 prevents …

WebHuman Monocyte STING Activation Flow Cytometry Panel 1 Kit #69210 (50 assays) Description: The Human Monocyte STING Activation Flow Cytometry Panel includes antibodies targeting phospho-STING (Ser366) and phenotyping markers to enable observation of STING activation in human monocyte populations among peripheral blood … WebJun 3, 2024 · Upon binding to cGAMP, activated STING undergoes a conformational change, oligomerizes, traffics through the Golgi, and recruits the kinase TBK1, which phosphorylates STING at ser366 as well as itself at ser172 ( Liu et al., …

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WebPhospho-STING (Ser365) Antibody (PA5-117271) in WB. Western blot analysis of extracts of THP-1 cells using Phospho-STING (Ser365) Polyclonal Antibody (Product # PA5-117271). … WebInterestingly, we found that STING interacts with both TBK1 and IRF3, and that mutations in STING that selectively disrupt its binding to IRF3 abrogate IRF3 phosphorylation without impairing TBK1 activation. ... IRF3 also bound to phospho-TBK1 [TRAF family member-associated NFκB activator (TANK)-binding kinase] (Fig. 4 E and G), which is a ...

WebJul 7, 2024 · Phospho-S365 acts as a docking site for IRF3, a transcription factor that is phosphorylated and activated by TBK1, leading to transcriptional induction of type I interferons (IFNs). Type I IFNs... WebNational Center for Biotechnology Information

WebJan 29, 2015 · STING is an essential adaptor protein in the cytosolic DNA sensing pathway that also activates IRF3 . Recently, STING Ser 366 was shown to be important in IRF3 … Phospho-STING (Ser366) (D7C3S) Rabbit mAb recognizes endogenous levels of STING protein only when phosphorylated at Ser366. Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser366 of human STING protein. Background

WebPhospho-STING (Ser365) Antibody (PA5-117271) in WB Western blot analysis of extracts of THP-1 cells using Phospho-STING (Ser365) Polyclonal Antibody (Product # PA5-117271). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10,000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Product Details

WebThe Human Monocyte STING Activation Flow Cytometry Panel includes antibodies targeting phospho-STING (Ser366) and phenotyping markers to enable observation of STING activation in human monocyte populations among peripheral blood mononuclear cells (PBMCs). CD45 is a pan leukocyte marker. Monocytes and dendritic cells (DCs) are … bisd eforceWebWestern blot analysis of extracts of THP-1 cells using Phospho-STING (Ser366) Polyclonal Antibody ( Product # PA5-117276 ). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10,000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in … bisd electionsWebInhibition of IDH3α enhanced the efficacy of chemoimmunotherapy by activating cGAS-STING pathway through regulating acidic tumor microenvironments. Preprint on Research Square on 11 October 2024 by Zhang, L., Dai, X., et al.. bisd election resultsWebMar 25, 2024 · N Immunoblots of Cit-H3, STING, cleaved caspase 3, caspase 3, cleaved Gasdermin D, Gasdermin D, phospho-MLKL, MLKL, phospho-γH2AX, and ZBP1 in the lung of WT mice exposed to diABZI alone or ... b is defined as the vessel whichWebA phosphate test measures the amount of phosphate in your blood. If that sounds too simple, stay tuned for a slight curveball. Phosphate is what you get when you combine the … dark cherry wood nightstandWebImmunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-STING antibody [SP338] (ab227704) Formalin-fixed, paraffin-embedded human lung squamous … bis demon warlockWebJun 7, 2024 · During this process, TBK1 also phosphorylates STING at Ser365, generating the IRF3-docking site on STING 13. STING is also phosphorylated at Ser365 by ULK1, and this phosphorylation is... dark cherry wood kitchen